Document Detail

Clinical criteria for vascular dementia: the NINDS-AIREN criteria.
MedLine Citation:
PMID:  8087178     Owner:  NLM     Status:  MEDLINE    
Vascular dementia (VAD) is the second most common cause of dementia. In addition, cerebrovascular disease (CVD) coexists with other causes, including Alzheimer's disease. Cognitive impairment related to CVD may be preventable, and these patients could benefit from therapy. This emphasizes the need for early detection, diagnostic consistency and accuracy of the clinical diagnosis of VAD. A number of current limitations in our knowledge about VAD have restricted the construction of clinical criteria, especially the concept of a behavioral syndrome due to vascular factors affecting the brain, and the main pathophysiological factors related to VAD. The latter include the type, extent, location and tempo of vascular brain lesions, as well as the causality between brain lesions and cognitive impairment. However, relevant information on VAD is beginning to emerge. The NINDS-AIREN Workshop on VAD made an attempt to facilitate international discussion and cooperation by defining consequences of CVD and the criteria for the VAD syndrome, for epidemiological and clinical studies. Here the concepts, pathophysiological factors, current conceptual barriers, and the criteria for the clinical diagnosis are reviewed.
T Erkinjuntti
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Dementia (Basel, Switzerland)     Volume:  5     ISSN:  1013-7424     ISO Abbreviation:  Dementia     Publication Date:    1994 May-Aug
Date Detail:
Created Date:  1994-10-20     Completed Date:  1994-10-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9010348     Medline TA:  Dementia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  189-92     Citation Subset:  IM    
Department of Neurology, University of Helsinki, Finland.
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MeSH Terms
Dementia, Vascular / diagnosis*,  physiopathology,  psychology

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