| Clinical course and risk stratification of myocardial infarct survivors with three-vessel disease. | |
| | |
MedLine Citation:
|
PMID: 3788767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Prevalence of three-vessel disease was prospectively analyzed in a series of 462 consecutive infarct survivors aged 60 years or less. Eighty-seven percent (403) of the patients were catheterized within one month of the acute event, and were followed for a mean of 43 months (range 21 to 69). Three-vessel disease was present in 96 cases (24%) and these patients form the study population. The primary goals of this study were to determine the prevalence of three-vessel disease and to identify predictors of survival and new coronary events among this subset of infarct survivors. During follow-up, 15 patients died, 17 had a recurrent nonfatal infarction, and 54 developed angina (4-year probability of each cardiac event being 0.20, 0.22, and 0.59, respectively). Cox's stepwise multivariate analysis identified the ejection fraction (EF) as the only predictor of survival (p less than 0.001). No predictors for nonfatal ischemic events were found among the independent variables considered. Patients were stratified in risk categories according to the EF. Four-year probability of survival was 1.0 in participants with EF = greater than 50% (n = 23), 0.77 for those with EF = 21% to 49% (n = 66), and 0.22 in patients with more severe left ventricular dysfunction, EF = less than 20% (n = 7). Probability of occurrence of nonfatal reinfarction or angina was similar in the three risk categories. Thus, our results indicate that a normal ejection fraction is found in 25% of infarct survivors with three-vessel disease, and that this subset of patients has a low incidence of early and intermediate range coronary events. |
| | |
Authors:
|
A Castaner; A Betriu; E Roig; S Coll; T de Flores; J Magrina; A Serra; J Bassaganyes; G Sanz |
Related Documents
:
|
11517817 - Identifying all suspects: case studies. 11759847 - Surveillance of ischaemic heart disease: results from the italian monica populations. 18082507 - Predictive value of coronary calcifications for future cardiac events in asymptomatic i... 16014347 - Derivation and validation of a disease-specific risk score for cardiac risk stratificat... 12660677 - Troponin i elevation and cardiac events after percutaneous coronary intervention. 8401367 - Cyclophosphamide cardiac injury mimicking acute myocardial infarction. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American heart journal Volume: 112 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1986 Dec |
Date Detail:
|
Created Date: 1986-12-30 Completed Date: 1986-12-30 Revised Date: 2006-02-27 |
Medline Journal Info:
|
Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1201-9 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angina Pectoris
/
epidemiology Coronary Angiography Coronary Disease / diagnosis*, epidemiology, mortality Exercise Test Follow-Up Studies Heart Catheterization Humans Male Middle Aged Myocardial Infarction / diagnosis*, mortality Myocardial Revascularization Prospective Studies Recurrence Risk Spain Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of Fluosol-DA on infarct morphology and vulnerability to ventricular arrhythmia.
Next Document: Anterior ST segment depression in acute inferior myocardial infarction as a marker of greater inferi...