| Clinical consequences of inadequate inhalation technique in asthma therapy. | |
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MedLine Citation:
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PMID: 3817076 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The FEV1-increase after inhalation of a beta 2-stimulant metered-dose aerosol was studied in 23 patients treated by specialists. The effect of their spontaneous inhalation technique was compared with that of controlled inhalation, which was optimised by means of a device controlling the breathing pattern and release of the metered-dose aerosol. This allowed quantitative assessment of the loss of bronchodilatation caused by the spontaneous inhalation technique. Thirteen patients who were observed to make inhalation errors showed a significant loss of bronchodilatation (30%), whereas ten patients who were observed to make no inhalation errors showed an insignificant loss of bronchodilatation (13%). It is concluded that when a metered-dose aerosol is used in general clinical practice there is a considerable loss of potential efficacy. |
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Authors:
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S Lindgren; B Bake; S Larsson |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of respiratory diseases Volume: 70 ISSN: 0106-4339 ISO Abbreviation: Eur J Respir Dis Publication Date: 1987 Feb |
Date Detail:
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Created Date: 1987-04-23 Completed Date: 1987-04-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006891 Medline TA: Eur J Respir Dis Country: DENMARK |
Other Details:
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Languages: eng Pagination: 93-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Inhalation Adult Aged Asthma / drug therapy* Humans Middle Aged Questionnaires Respiratory Function Tests Self Administration / methods Terbutaline / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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23031-25-6/Terbutaline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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