| Clinical commentary: Reaching new targets in monotherapy and combination therapy. | |
| | |
MedLine Citation:
|
PMID: 21291719 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Cardiovascular disease remains the most common cause of death in the United States. There has, however, been a decline in the age-adjusted death rate for coronary heart disease. This decline may be due, in part, to more aggressive treatment guidelines for treating cardiovascular risk factors, such as hypertension, diabetes, and dyslipidemia. The 2004 update to the National Cholesterol Education Program guidelines have recommended lower low-density lipoprotein cholesterol goals in high-risk patients. Based on the new targets for low-density lipoprotein cholesterol, clinicians will need more efficacious lipid-lowering therapies and improved options for combination therapy. Statin and statin-based combinations have been the mainstays of therapy during the last several years, and as statin utilization increases in the United States, more high-risk patients become exposed to potential statin intolerance. This commentary reviews statin-sparing combinations and use of cholesterol-absorption inhibitors. |
| | |
Authors:
|
Ryan C Neal |
Related Documents
:
|
7321829 - Comparison of serum lipids between habitually high and low active pre-adolescent males. 18932049 - Effect of dietary alpha-ketoglutarate on blood lipid profile during hypercholesterolaem... 8099379 - Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent rel... 3621949 - Lipid markers, coronary score and coronary artery disease of stable angina pectoris type. 16549459 - High cholesterol intake modifies chylomicron metabolism in normolipidemic young men. 10962519 - Association of hypertensive status and its drug treatment with lipid and haemostatic fa... 3819869 - Effects of dietary calcium and age on parathyroid hormone, calcitonin and serum and mil... 22444419 - Effect of supplementation of ewes with barley or maize during the last week of pregnanc... 2808169 - Effect of group size and feeding regimen on nutrient digestibility studies with weanlin... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of clinical lipidology Volume: 2 ISSN: 1933-2874 ISO Abbreviation: J Clin Lipidol Publication Date: 2008 Apr |
Date Detail:
|
Created Date: 2011-02-04 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101300157 Medline TA: J Clin Lipidol Country: United States |
Other Details:
|
Languages: eng Pagination: S34-8 Citation Subset: - |
Affiliation:
|
Baylor College of Medicine, Center for Cardiovascular Disease Prevention, 6565 Fannin, Suite B-160, Houston, TX 77030, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Interrupting bile-acid handling and lipid and glucose control: Effects of colesevelam on glucose lev...
Next Document: Dietary agents that target gastrointestinal and hepatic handling of bile acids and cholesterol.