Document Detail


Clinical characteristics of sudden cardiac death in patients with vasospastic angina.
MedLine Citation:
PMID:  2632824     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Of 383 patients with vasospastic angina who were followed for a period of 3.2 +/- 0.1 years, 9 (2%) died suddenly from cardiac causes. Calcium antagonists had been given to 98% of our patients. Only one patient who died suddenly had a fixed coronary stenosis of 75% or greater. Eight of the 9 patients showed ST segment elevation during anginal attack at rest, and 3 patients showed ST segment elevation at both anterior and inferior leads. Sudden death occurred in 6 of 41 patients (12.5%) who were documented to have multivessel coronary spasm, but in only 3 of 342 patients (1%) who had single vessel spasm (p less than 0.01). Serious arrhythmia occurred during anginal episode in 3 of 9 patients who died suddenly (53%) and in 52 of 374 who did not (14%). These results suggest that the frequency of sudden cardiac death was rather low in Japanese patients with vasospastic angina. The risk of sudden death was increased in patients with multivessel spasm and serious arrhythmia during anginal attacks but not these with fixed coronary stenosis.
Authors:
S Koyanagi; A Takeshita; M Nakamura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  53     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-05-18     Completed Date:  1990-05-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1541-5     Citation Subset:  IM    
Affiliation:
Research Institute of Angiocardiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Angina Pectoris, Variant / drug therapy,  mortality*
Arrhythmias, Cardiac / complications
Calcium Channel Blockers / therapeutic use
Death, Sudden / epidemiology,  etiology*
Female
Follow-Up Studies
Humans
Incidence
Japan / epidemiology
Male
Middle Aged
Risk Factors
Chemical
Reg. No./Substance:
0/Calcium Channel Blockers

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