| Clinical characteristics and outcome of current standard management of central retinal artery occlusion. | |
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MedLine Citation:
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PMID: 20584027 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To investigate the visual outcomes in acute central retinal artery occlusion (CRAO) with current standard therapy at two university teaching hospitals. METHODS: Retrospective analysis of two cohorts of CRAO patients from John Hopkins Hospital (JHH; USA), and Flinders Medical Centre (FMC; Australia), treated with current standard therapy. The outcome measures were visual acuity, and subsequent ocular and systemic ischaemic events. RESULTS: The mean follow-up period was 11.2 +/- 13.1 months in the JHH cohort and 35.4 +/- 34.9 months in the FMC cohort. The frequency distribution of vascular risk factors and the incidence of subsequent ischaemic events were similar for the patients from both institutions. All patients from JHH were treated as inpatients, whereas 79% of patients from FMC were treated as outpatients. More patients in the JHH cohort underwent paracentesis, ocular massage or were treated with intraocular hypotensive agents (76%) than in the FMC cohort (26%); however, there was no significant difference in visual outcome between the two cohorts (P = 0.114). CONCLUSION: Despite differences in management of CRAO between two institutions in different countries, visual outcomes were similar. This suggests a lack of efficacy of current standard treatment in acute CRAO. |
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Authors:
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Adam K Rudkin; Andrew W Lee; Eric Aldrich; Neil R Miller; Celia S Chen |
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Publication Detail:
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Type: Journal Article Date: 2010-03-02 |
Journal Detail:
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Title: Clinical & experimental ophthalmology Volume: 38 ISSN: 1442-9071 ISO Abbreviation: Clin. Experiment. Ophthalmol. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-23 Completed Date: 2010-11-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100896531 Medline TA: Clin Experiment Ophthalmol Country: Australia |
Other Details:
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Languages: eng Pagination: 496-501 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, NH & MRC Centre of Clinical Eye Research, South Australia, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Aged Aged, 80 and over Antihypertensive Agents / therapeutic use* Female Humans Incidence Inpatients Ischemia / epidemiology Male Massage / methods* Middle Aged Outpatients Paracentesis* Retinal Artery Occlusion / drug therapy*, epidemiology Retrospective Studies Risk Factors Treatment Outcome Visual Acuity Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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