Document Detail

Clinical characteristics of generalized idiopathic pruritus in patients from a tertiary referral center in Singapore.
MedLine Citation:
PMID:  17910707     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Generalized idiopathic pruritus is a rarely studied heterogeneous condition, where patients with non-inflamed, non-pathologic skin complain of widespread pruritus. METHODS: We had administered a detailed pruritus questionnaire, based on the short form of the McGill pain questionnaire, on 75 patients with this condition. RESULTS: All 75 patients recruited with generalized idiopathic pruritus completed the questionnaire. In 92% of the patients, pruritus appeared on a daily basis. Most patients experienced pruritus at night (56%) and in the evening (61%) and 69% had difficulty falling asleep. Pruritus mainly involved the legs (79%), arms (76%) and back (68%). Accompanying symptoms were heat sensation (17%) and pain (13%). 80% had been prescribed antihistamines, of whom 56% obtained short-term relief. The sensation of itch has been reported to be crawling (33%), tickling (20%), stinging (19%) and burning (19%). Patients also reported that the itch was unbearable (73%), bothersome (72%), annoying (67%) and worrisome (45%). The worst-state VAS scores were significantly higher in patients who reported agitation (P = 0.006), difficulty in concentration (P= 0.010) and anxiety (P= 0.033). CONCLUSION: This study describes the sensory and affective dimensions of generalized idiopathic pruritus, and this questionnaire has been found to be a useful tool for evaluating pruritus in this condition.
Anthony T-J Goon; Gil Yosipovitch; Yiong-Huak Chan; Chee-Leok Goh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  46     ISSN:  0011-9059     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-10-03     Completed Date:  2007-12-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1023-6     Citation Subset:  IM    
National Skin Centre and National University of Singapore, Singapore.
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MeSH Terms
Activities of Daily Living
Aged, 80 and over
Antipruritics / therapeutic use
Middle Aged
Paresthesia / epidemiology
Pruritus / complications,  epidemiology*,  psychology,  therapy
Quality of Life*
Severity of Illness Index
Singapore / epidemiology
Reg. No./Substance:

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