Document Detail


Clinical characteristics of early and late recurrent ischaemic stroke.
MedLine Citation:
PMID:  20496282     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: The aim of the study was to search for differences between clinical characteristics of recurrent ischaemic stroke which occurred within the fifth year after the first event or later, and early recurrence, i.e. within the first year after first-ever ischaemic stroke. We also tried to determine prognostic factors of late recurrent ischaemic episodes. MATERIAL AND METHODS: The patients were divided into two groups: group I comprised 124 individuals with recurrence within the first year, and group II - 98 individuals in whom the recurrent episode appeared within the fifth year or later. RESULTS: A significantly higher percentage of patients in group I demonstrated evident stenosis (70% or more) of internal carotid artery ipsilateral to stroke (p = 0.023). In this group more cardioembolic strokes were found compared to group II, while in the latter, predominantly lacunar strokes appeared (p = 0.046 and 0.0002, respectively). Group II patients significantly more frequently reported acetylsalicylic acid application, including systematic drug use (p = 0.001). No evident differences were found between groups considering other important non-modifiable and modifiable risk factors of stroke. CONCLUSIONS: Small differences between risk factors of ischaemic stroke profiles in patients with early and late recurrent episodes do not allow us to distinguish unequivocally a group of patients with better prognosis regarding the time of recurrent stroke. Use of antiplatelet drugs, either systematic or non-systematic, and lacunar stroke are independent, positive prognostic factors of delay of potential recurrent stroke.
Authors:
Przemysław Nowacki; Anna Bajer-Czajkowska; Marta Masztalewicz
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Neurologia i neurochirurgia polska     Volume:  44     ISSN:  0028-3843     ISO Abbreviation:  Neurol. Neurochir. Pol.     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-05-24     Completed Date:  2010-07-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0101265     Medline TA:  Neurol Neurochir Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  123-30     Citation Subset:  IM    
Affiliation:
Katedra i Neurologii, Pomorska Akademia Medyczna w Szczecinie. nowacprz@sci.pam.szczecin.pl
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MeSH Terms
Descriptor/Qualifier:
Aged
Aspirin / therapeutic use
Brain Infarction / epidemiology*,  prevention & control
Carotid Artery, Internal
Carotid Stenosis / epidemiology*
Causality
Comorbidity
Disease Progression
Female
Follow-Up Studies
Humans
Male
Middle Aged
Platelet Aggregation Inhibitors / therapeutic use
Prognosis
Prospective Studies
Recurrence
Risk Factors
Survival Analysis
Chemical
Reg. No./Substance:
0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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