| Clinical characteristics, ballooning pattern, and long-term prognosis of transient left ventricular ballooning syndrome. | |
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MedLine Citation:
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PMID: 20457338 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Although patients with transient left ventricular ballooning syndrome (TLVBS), also known as Takotsubo cardiomyopathy, improve rapidly and recover left ventricular systolic function, the long-term prognosis is not well-known. This study investigated the clinical features of TLVBS, and its in-hospital and long-term (in-hospital plus postdischarge) mortality. METHODS AND RESULTS: We evaluated 87 patients diagnosed with TLVBS. The median follow-up was 42 months (interquartile range, 19 to 72 months). During follow-up, no recurrences were reported, but 20 (23%) patients died. Two nonsurvivors (2%) were suspected of dying from sudden cardiac death. The in-hospital total mortality rate was 9%, but the in-hospital cardiac mortality rate was 0%. Most deaths were associated with underlying noncardiac diseases. Baseline characteristics were mostly similar between survivors and nonsurvivors. However, nonsurvivors were older, and more likely to be smokers compared with survivors. Underlying noncardiac diseases were the only independent predictors of long-term mortality (hazard ratio, 3.954; 95% confidence interval, 1.369 to 11.422; P=.011). There were no significant differences in long-term mortality, according to the preceding stress events or ballooning patterns. CONCLUSIONS: Although a substantial number of patients with TLVBS die, the long-term cardiac mortality is low. The severity of heart failure owing to TLVBS may influence in-hospital mortality, whereas underlying noncardiac diseases have a more significant correlation with the long-term prognosis than does TLVBS itself. |
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Authors:
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Bong Gun Song; Joo-Yong Hahn; Soo Jin Cho; Young Hwan Park; Seung Min Choi; Ji Han Park; Seung-Hyuk Choi; Jin-Ho Choi; Seung Woo Park; Sang Hoon Lee; Hyeon-Cheol Gwon |
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Publication Detail:
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Type: Journal Article Date: 2009-10-02 |
Journal Detail:
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Title: Heart & lung : the journal of critical care Volume: 39 ISSN: 1527-3288 ISO Abbreviation: Heart Lung Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-05-11 Completed Date: 2011-06-02 Revised Date: 2011-10-13 |
Medline Journal Info:
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Nlm Unique ID: 0330057 Medline TA: Heart Lung Country: United States |
Other Details:
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Languages: eng Pagination: 188-95 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam-gu, Seoul, Republic of Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Aged Aged, 80 and over Confidence Intervals Female Humans Male Middle Aged Multivariate Analysis Prognosis Proportional Hazards Models Republic of Korea Retrospective Studies Risk Factors Severity of Illness Index Takotsubo Cardiomyopathy / diagnosis*, mortality, pathology Time Factors |
| Comments/Corrections | |
Comment In:
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Heart Lung. 2011 Sep-Oct;40(5):472
[PMID:
20723983
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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