| Clinical cardiac magnetic resonance spectroscopy. | |
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MedLine Citation:
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PMID: 22014498 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac magnetic resonance spectroscopy (MRS) is a noninvasive tool for the assessment of myocardial metabolism, without the use of radiation or intravenous contrast agents. Using the intrinsic magnetic resonance signals from nuclei, including (31)Phosphorus, (1)Hydrogen, (23)Sodium, and (13)Carbon and, more recently, hyperpolarization techniques, MRS provides a comprehensive metabolic assessment of cardiac muscle. This highly versatile technique has provided insights into the pathophysiology of cardiac metabolism in a wide range of conditions, including ischemic heart disease, heart failure, genetic cardiomyopathies, heart transplantation, hypertensive heart disease, valvular heart disease, and diabetes. In addition, MRS has value in the assessment of prognosis and for monitoring therapeutic strategies in heart failure. However, because of the low temporal and spatial resolution of the technique, MRS has so far been limited to research applications. With higher field strength magnets and novel hyperpolarization techniques, the promise of using MRS for clinical applications may eventually be fulfilled. |
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Authors:
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Cameron J Holloway; Joseph Suttie; Sairia Dass; Stefan Neubauer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Progress in cardiovascular diseases Volume: 54 ISSN: 1532-8643 ISO Abbreviation: Prog Cardiovasc Dis Publication Date: 2011 Nov-Dec |
Date Detail:
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Created Date: 2011-10-21 Completed Date: 2011-12-06 Revised Date: 2012-02-13 |
Medline Journal Info:
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Nlm Unique ID: 0376442 Medline TA: Prog Cardiovasc Dis Country: United States |
Other Details:
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Languages: eng Pagination: 320-7 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Cardiovascular Medicine, The University of Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford, UK. cameron.holloway@dpag.ox.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Energy Metabolism* Heart Diseases / diagnosis*, metabolism, physiopathology, therapy Humans Magnetic Resonance Spectroscopy* Myocardium / metabolism* Predictive Value of Tests Prognosis Severity of Illness Index |
| Grant Support | |
ID/Acronym/Agency:
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//British Heart Foundation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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