| Clinical biochemistry of pregnancy. | |
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MedLine Citation:
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PMID: 9055057 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Major adaptations in maternal physiology and metabolism are required for successful pregnancy outcome. Hormonal changes initiated even before conception significantly alter maternal biochemistry early in pregnancy. Steroid hormones, peptide hormones, and prostaglandins interact to expand blood and plasma volume and modulate the maternal capacity to supply energy and nutrients to the fetoplacental unit. As gestation progresses, reference ranges for the concentration of many biochemical parameters change significantly from those found in the nonpregnant state. Gestation-specific reference ranges are essential for correct interpretation of tests used in screening, diagnosis, and monitoring during pregnancy. The use of clinical laboratory tests in the management of high-risk pregnancy are discussed from the perspective of testing before conception and during pregnancy. |
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Authors:
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G Lockitch |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Critical reviews in clinical laboratory sciences Volume: 34 ISSN: 1040-8363 ISO Abbreviation: Crit Rev Clin Lab Sci Publication Date: 1997 |
Date Detail:
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Created Date: 1997-05-20 Completed Date: 1997-05-20 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8914816 Medline TA: Crit Rev Clin Lab Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 67-139 Citation Subset: IM |
Affiliation:
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Department of Pathology and Laboratory Medicine, University of British Columbia, Canada. kidsug@unixg.ubc.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological Female Hormones / metabolism Humans Pregnancy / metabolism*, physiology Pregnancy Complications / diagnosis Reference Values |
| Chemical | |
Reg. No./Substance:
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0/Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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