| Clinical assessment of the effect of digital filtering on the detection of ventricular late potentials. | |
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MedLine Citation:
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PMID: 12426627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ventricular late potentials are low-amplitude signals originating from damaged myocardium and detected on the body surface by ECG filtering and averaging. Digital filters present in commercial equipment may interfere with the ability of arrhythmia stratification. We compared 40-Hz BiSpec (BI) and classical 40- to 250-Hz band-pass Butterworth bidirectional (BD) filters in terms of impact on time domain variables and diagnostic properties. In a transverse retrospective age-adjusted case-control study, 221 subjects with sinus rhythm without bundle branch block were divided into three groups after signal-averaged ECG acquisition: GI (N = 40), clinically normal controls, GII (N = 158), subjects with coronary heart disease without sustained monomorphic ventricular tachycardia (SMVT), and GIII (N = 23), subjects with heart disease and documented SMVT. Conventional variables analyzed from vector magnitude data after averaging to 0.3 micro V final noise were obtained by application of each filter to the averaged signal, and evaluated in pairs by numerical comparison and by diagnostic agreement assessment, using conventional and optimized thresholds of normality. Significant differences were found between BI and BD variables in all groups, with diagnostic results showing significant disagreement between both filters [kappa value of 0.61 (P<0.05) for GII and 0.31 for GIII (P = NS)]. Sensitivity for SMVT was lower with BI than with BD (65.2 vs 91.3%, respectively, P<0.05). Filters provided significantly different numerical and diagnostic results and the BI filter showed only limited clinical application to risk stratification of ventricular arrhythmia. |
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Authors:
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P R Benchimol-Barbosa; P R B Barbosa; E C Barbosa; A S Bomfim; P Ginefra; J Nadal |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] Volume: 35 ISSN: 0100-879X ISO Abbreviation: Braz. J. Med. Biol. Res. Publication Date: 2002 Nov |
Date Detail:
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Created Date: 2002-11-11 Completed Date: 2003-04-02 Revised Date: 2008-11-04 |
Medline Journal Info:
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Nlm Unique ID: 8112917 Medline TA: Braz J Med Biol Res Country: Brazil |
Other Details:
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Languages: eng Pagination: 1285-92 Citation Subset: IM |
Affiliation:
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Programa de Engenharia Biomédica, COPPE, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. pbbarbo@attglobal.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Distribution Analysis of Variance Arrhythmias, Cardiac / diagnosis*, physiopathology Case-Control Studies Cohort Studies Electrocardiography / methods* Evoked Potentials / physiology* Female Humans Male Retrospective Studies Sensitivity and Specificity Signal Processing, Computer-Assisted / instrumentation* Ventricular Dysfunction / diagnosis*, physiopathology |
| Comments/Corrections | |
Erratum In:
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Braz J Med Biol Res. 2007 Oct;40(10):1418 Note: Barbosa, P R B [corrected to Benchimol-Barbosa, P R] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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