| Clinical assessment of blood glucose homeostasis in horses: comparison of a continuous glucose monitoring system with a combined intravenous glucose and insulin test protocol. | |
| | |
MedLine Citation:
|
PMID: 21223373 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Background: The combined glucose-insulin test (CGIT) is helpful for evaluating insulin sensitivity. A continuous glucose monitoring system (CGMS) reports changes in interstitial glucose concentrations as they occur in the blood. Use of the CGMS minimizes animal contact and may be useful when performing a CGIT. Hypothesis: Results obtained using a CGMS are useful for the evaluation of glucose responses during the evaluation of insulin sensitivity in equids. Animals: Seven mature, obese ponies. Methods: Ponies were equipped with CGMS for determination of interstitial glucose concentrations. Glucose (150 mg/kg, IV) and insulin (0.1 U/kg, IV) were administered and blood glucose concentrations determined at (minutes after time zero) 1, 5, 15, 25, 35, 45, 60, 75, 90, 105, and 120 with a hand-held glucometer. Blood chemistry results were compared with simultaneously obtained results using CGMS. Results: Concordance coefficients determined for comparison of blood glucose concentrations determined by a hand-held glucometer and those determined by CGMS after the zero time point were 0.623, 0.764, 0.834, 0.854, and 0.818 (for delays of 0, 5, 10, 15, and 20 minutes, respectively). Conclusions and Clinical Importance: Interstitial glucose concentrations obtained by the CGMS compared favorably to blood glucose concentrations. CGMS may be useful for assessment of glucose dynamics in the CGIT. |
| | |
Authors:
|
P J Johnson; C E Wiedmeyer; A Lacarrubba; N T Messer; H A Dingfelder; A M Cogswell; J R R Amorim; V K Ganjam |
Related Documents
:
|
10492053 - Correlation of acetylator phenotype with peripheral, autonomic and central neuropathy i... 6299013 - Occupational peripheral neuropathies. 8645373 - Hypercoagulability and high lipoprotein(a) levels in patients with type ii diabetes mel... |
Publication Detail:
|
Type: Journal Article Date: 2010-12-08 |
Journal Detail:
|
Title: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine Volume: 25 ISSN: 1939-1676 ISO Abbreviation: J. Vet. Intern. Med. Publication Date: 2011 Jan-Feb |
Date Detail:
|
Created Date: 2011-01-12 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8708660 Medline TA: J Vet Intern Med Country: United States |
Other Details:
|
Languages: eng Pagination: 162-5 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 by the American College of Veterinary Internal Medicine. |
Affiliation:
|
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evaluation of potential medical and economic benefits of universal rotavirus vaccination in Greece.
Next Document: Short- and Long-Term Follow-up of Percutaneous Coronary Intervention for Chronic Total Occlusion thr...