Document Detail

Clinical applications of thrombolytic therapy.
MedLine Citation:
PMID:  8900363     Owner:  NLM     Status:  MEDLINE    
Although thrombolytic therapy is used in a variety of settings, it has gained the most prominence in the treatment of myocardial infarction. The effectiveness of thrombolytic agents in reducing mortality in patients who present with myocardial infarction has been clearly demonstrated by large-scale studies. Unfortunately, only a minority of patients who present with myocardial infarction are currently receiving thrombolytic therapy. Many patients who could benefit from thrombolysis are unnecessarily excluded from treatment. It is now recommended that all patients who have appropriate electrocardiographic changes and present within 12 hours of the onset of acute myocardial infarction be considered for thrombolytic therapy. Factors such as age and history of previous myocardial infarction are no longer viewed as barriers to treatment.
F S Mair
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American family physician     Volume:  54     ISSN:  0002-838X     ISO Abbreviation:  Am Fam Physician     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1996-12-04     Completed Date:  1996-12-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2041-8     Citation Subset:  AIM; IM    
University of Kansas Medical Center, Kansas City, USA.
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MeSH Terms
Brain Ischemia / drug therapy
Fibrinolytic Agents / therapeutic use
Myocardial Infarction / drug therapy*
Patient Selection
Pulmonary Embolism / drug therapy
Streptokinase / therapeutic use
Thrombolytic Therapy* / contraindications
Reg. No./Substance:
0/Fibrinolytic Agents; EC 3.4.-/Streptokinase
Comment In:
Am Fam Physician. 1997 Sep 1;56(3):738, 741   [PMID:  9301568 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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