Document Detail

Clinical applications of the sustained-release dexamethasone implant for treatment of macular edema.
MedLine Citation:
PMID:  21383939     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Macular edema is one of the leading causes of vision loss among patients with retinal vein occlusion, diabetic retinopathy, and posterior chamber inflammatory disease. However, the treatment of macular edema is considerably limited by the difficulty in delivering effective doses of therapeutic agents into the vitreous cavity. In recent years, the development of a sustained-release dexamethasone intravitreal implant (Ozurdex(®)) has enabled more controlled drug release at a stable rate over a long period of time, with a potentially lower rate of adverse events. Clinical studies indicate that this dexamethasone implant is a promising new treatment option for patients with persistent macular edema resulting from retinal vein occlusion, diabetic retinopathy, and uveitis or Irvine-Gass syndrome.
Rocío Herrero-Vanrell; Jose Augusto Cardillo; Baruch D Kuppermann
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Publication Detail:
Type:  Journal Article     Date:  2011-02-01
Journal Detail:
Title:  Clinical ophthalmology (Auckland, N.Z.)     Volume:  5     ISSN:  1177-5483     ISO Abbreviation:  Clin Ophthalmol     Publication Date:  2011  
Date Detail:
Created Date:  2011-03-08     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101321512     Medline TA:  Clin Ophthalmol     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  139-46     Citation Subset:  -    
Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Complutense University, Madrid, Spain;
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