Document Detail


Clinical applications of immunohistochemistry in gynecological malignancies.
MedLine Citation:
PMID:  17362308     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Over the past two decades, immunohistochemical techniques have improved to such a degree that it is now a common adjuvant test to the traditional hematoxylin and eosin-stained histologic sections. It is used in most realms of surgical pathology and can often aid in final diagnosis and, in some cases, prognosis. However, immunohistochemistry (IHC) is not always helpful and many pitfalls to its use exist. Understanding the basics of IHC, its utility and difficulties will aid clinicians in better understanding how diagnoses are rendered. This study reviews the general principles of IHC and demonstrates its utility with several commonly encountered problematic areas in gynecological pathology.
Authors:
J Shutter; K A Atkins; K Ghartey; T J Herzog
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society     Volume:  17     ISSN:  1048-891X     ISO Abbreviation:  Int. J. Gynecol. Cancer     Publication Date:    2007 Mar-Apr
Date Detail:
Created Date:  2007-03-16     Completed Date:  2007-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111626     Medline TA:  Int J Gynecol Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  311-5     Citation Subset:  IM    
Affiliation:
George Washington University, USA.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma / diagnosis*,  pathology*,  secondary
Cost-Benefit Analysis
Cyclin-Dependent Kinase Inhibitor p16 / analysis
Female
Genital Neoplasms, Female / diagnosis*,  pathology*,  secondary
Humans
Immunohistochemistry / economics,  methods*
Keratin-20 / analysis
Keratin-7 / analysis
Neoplasms, Unknown Primary / diagnosis
Chemical
Reg. No./Substance:
0/Cyclin-Dependent Kinase Inhibitor p16; 0/Keratin-20; 0/Keratin-7

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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