| Clinical applications of diffusion tensor imaging and tractography in children. | |
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MedLine Citation:
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PMID: 17598098 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diffusion tensor imaging (DTI) is a relatively new addition to routine MR imaging. DTI exploits the preferential movement of water protons within the brain along the axis of the axons. This anisotropic diffusion provides information about the immature brain prior to myelination, during maturation, and in normal and disease states, information that MRI cannot provide. By virtue of sensitivity to anisotropic movement of protons, DTI allows the core of larger individual white matter tracts to be visualized as discreet anatomic structures. DTI can also provide information about the microarchitecture of white matter in the form of metrics referred to as fractional anisotropy and diffusivity. The information contained within the diffusion tensor data can be used to create 3-D mathematical renderings of white matter or tractography. This article is an introduction to DTI for pediatric radiologists interested in exploring potential applications in children. |
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Authors:
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Nancy K Rollins |
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Publication Detail:
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Type: Journal Article; Review Date: 2007-06-28 |
Journal Detail:
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Title: Pediatric radiology Volume: 37 ISSN: 0301-0449 ISO Abbreviation: Pediatr Radiol Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-07-10 Completed Date: 2008-01-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0365332 Medline TA: Pediatr Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 769-80 Citation Subset: IM |
Affiliation:
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Children's Medical Center of Dallas, University of Texas Southwestern Medical Center, 1935 Motor St., Dallas, TX 75235, USA. nancy.rollins@childrens.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anisotropy Brain / abnormalities* Brain Diseases / diagnosis* Brain Mapping / methods* Child Child, Preschool Diffusion Magnetic Resonance Imaging* Humans Image Interpretation, Computer-Assisted Imaging, Three-Dimensional Infant Infant, Newborn Nerve Fibers, Myelinated / ultrastructure* Neural Pathways / ultrastructure* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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