Document Detail


Clinical applications and advances of positron emission tomography with fluorine-18-fluorodeoxyglucose (18F-FDG) in the diagnosis of liver neoplasms.
MedLine Citation:
PMID:  18508981     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Positron emission tomography (PET) using 18F-fluorodeoxyglucose (18F-FDG) has been widely used not only for detecting and staging malignant tumours but also for monitoring therapy response and for differentiating malignant lesions from benign lesions. However, the sensitivity of 18F-FDG PET for hepatocellular carcinoma (HCC) is low. Recent research about the novel drug shows that the sensitivity of 11C-acetate PET for HCC is higher than that of 18F-FDG PET and 11C-acetate also indicates tumour cell differentiation. 18F-FDG PET proved to be highly sensitive in detecting hepatic metastases from different primaries. 18F-FDG PET has also been shown to be useful and more accurate than conventional imaging modalities in demonstrating the effect of local treatments in liver tumours. With the development of small animal imaging, animal research about 18F-FDG PET is increasing.
Authors:
Y-x He; Q-y Guo
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  84     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-29     Completed Date:  2008-12-04     Revised Date:  2009-10-22    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  246-51     Citation Subset:  IM    
Affiliation:
Department of Radiology, The Shengjing Hospital (The Second Affiliated Hospital), China Medical University, Shenyang City, Liaoning Province, 110004, PR China.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Hepatocellular / radionuclide imaging*
Cholangiocarcinoma / radionuclide imaging*
Fluorodeoxyglucose F18 / diagnostic use*,  metabolism
Humans
Liver Neoplasms / radionuclide imaging*,  secondary
Positron-Emission Tomography / methods*
Radiopharmaceuticals / diagnostic use*,  metabolism
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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