Document Detail

Clinical applications of ECG-gated myocardial perfusion SPECT.
MedLine Citation:
PMID:  17106175     Owner:  NLM     Status:  MEDLINE    
Erectrocardiogram (ECG)-gated myocardial perfusion single photon emission computed tomography (SPECT) can be used to assess myocardial perfusion and left ventricular function simultaneously. Various clinical applications of gated SPECT and their usefulness have been reported. The functional variables that can be determined with gated SPECT have been limited to systolic indices. Therefore, we evaluated left ventricular diastolic function with gated SPECT using data obtained from various frames per cardiac cycle and found that date generated from 32-frames are suitable for clinical use. Serial assessment of left ventricular function was also performed during bicycle exercise and dobutamine stress by means of gated SPECT using short-time data collection. These techniques, therefore, have the potential to provide useful information for evaluating myocardial conditions, such as hibernation and residual ischemia in infarct areas. Recently, we have developed a new technique for three-dimensional registration of CT coronary angiography (CTCA) and ECG-gated myocardial perfusion SPECT. This technique of registration may assist the integration of information from gated SPECT and CTCA and may have clinical application for the diagnosis of ischemic heart disease. These various applications would contribute to the development of nuclear cardiology.
Shin-ichiro Kumita; Keiichi Cho; Hidenobu Nakajo; Masahiro Toba; Yoshimitsu Fukushima; Sunao Mizumura; Tatsuo Kumazaki
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of Nippon Medical School = Nippon Ika Daigaku zasshi     Volume:  73     ISSN:  1345-4676     ISO Abbreviation:  J Nippon Med Sch     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-11-19     Completed Date:  2007-02-09     Revised Date:  2012-09-25    
Medline Journal Info:
Nlm Unique ID:  100935589     Medline TA:  J Nippon Med Sch     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  248-57     Citation Subset:  IM    
Department of Clinical Radiology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan.
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MeSH Terms
Coronary Angiography
Dobutamine / diagnostic use
Exercise Test
Fatty Acids / metabolism
Myocardial Ischemia / diagnosis
Tomography, Emission-Computed, Single-Photon / methods*
Tomography, X-Ray Computed
Ventricular Function, Left / physiology*
Reg. No./Substance:
0/Fatty Acids; 34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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