Document Detail

Clinical application of the rapid pneumococcal urinary antigen test in the treatment of severe pneumonia in children.
MedLine Citation:
PMID:  18327425     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: To evaluate the efficacy of the pneumococcal urinary antigen test (PUAT) in severe pediatric pneumonia. METHODS: The study enrolled 245 pediatric patients with severe pneumonia. Patients were divided into four groups; groups 1 and 2 received PUAT, while groups 3 and 4 did not. Additionally, PUAT-positive group 1 patients were treated with penicillin, while PUAT-negative patients received ampicillin-sulbactam or cefuroxime. Group 2 patients were treated empirically without following the group 1 protocol. Group 3 patients were treated following the guideline of the Infectious Diseases Society of Taiwan (IDST), and group 4 patients were treated empirically without following the IDST guideline. Treatment was assessed by the duration of fever. RESULTS: Treatment was most effective for group 1 and least effective for group 4. Group 2 treatment was superior to group 3 treatment. Multivariate regression analysis of groups 1 and 2 revealed that the use of PUAT (groups 1 and 2) was associated with superior response in comparison with group 4. CONCLUSION: Application of PUAT and adequate antimicrobial treatments in the initial stage for pediatric patients with severe pneumonia resulted in improved outcome as assessed by shortening of the duration of fever.
Huey-Fung Cheong; Luo-Ping Ger; Ming-Ting Wu; Chih-Pei Sun; Kai-Sheng Hsieh; Yung-Ching Liu; Ming-Fang Cheng
Related Documents :
10077045 - Erythromycin enhances early postoperative contractility of the denervated whole stomach...
24831525 - Fixed bearing lateral unicompartmental knee arthroplasty-short to midterm survivorship ...
25097505 - Catheter indwell time and phlebitis development during peripheral intravenous catheter ...
22323495 - Mitral valve repair for severe mitral regurgitation secondary to lone atrial fibrillation.
25341695 - Total facial nerve decompression in severe idiopathic recurrent facial palsy.
20561685 - Intraocular lens stability and refractive outcomes after cataract surgery using primary...
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi     Volume:  41     ISSN:  1684-1182     ISO Abbreviation:  J Microbiol Immunol Infect     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-10     Completed Date:  2008-08-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100956211     Medline TA:  J Microbiol Immunol Infect     Country:  China    
Other Details:
Languages:  eng     Pagination:  41-7     Citation Subset:  IM    
Department of Pediatrics, Pingtung Christian Hospital, Pingtung, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antigens, Bacterial / urine*
Child, Preschool
Fever / diagnosis,  drug therapy
Immunologic Tests / methods*
Infant, Newborn
Pneumonia, Pneumococcal / diagnosis,  drug therapy*,  pathology
Streptococcus pneumoniae / immunology*,  isolation & purification
Treatment Outcome
Reg. No./Substance:
0/Antigens, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Low rate of nasopharyngeal carriage and high rate of ampicillin resistance for Haemophilus influenza...
Next Document:  Clinical features and prognostic factors in childhood pneumococcal meningitis.