| Clinical application of the rapid pneumococcal urinary antigen test in the treatment of severe pneumonia in children. | |
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MedLine Citation:
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PMID: 18327425 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: To evaluate the efficacy of the pneumococcal urinary antigen test (PUAT) in severe pediatric pneumonia. METHODS: The study enrolled 245 pediatric patients with severe pneumonia. Patients were divided into four groups; groups 1 and 2 received PUAT, while groups 3 and 4 did not. Additionally, PUAT-positive group 1 patients were treated with penicillin, while PUAT-negative patients received ampicillin-sulbactam or cefuroxime. Group 2 patients were treated empirically without following the group 1 protocol. Group 3 patients were treated following the guideline of the Infectious Diseases Society of Taiwan (IDST), and group 4 patients were treated empirically without following the IDST guideline. Treatment was assessed by the duration of fever. RESULTS: Treatment was most effective for group 1 and least effective for group 4. Group 2 treatment was superior to group 3 treatment. Multivariate regression analysis of groups 1 and 2 revealed that the use of PUAT (groups 1 and 2) was associated with superior response in comparison with group 4. CONCLUSION: Application of PUAT and adequate antimicrobial treatments in the initial stage for pediatric patients with severe pneumonia resulted in improved outcome as assessed by shortening of the duration of fever. |
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Authors:
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Huey-Fung Cheong; Luo-Ping Ger; Ming-Ting Wu; Chih-Pei Sun; Kai-Sheng Hsieh; Yung-Ching Liu; Ming-Fang Cheng |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi Volume: 41 ISSN: 1684-1182 ISO Abbreviation: J Microbiol Immunol Infect Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-03-10 Completed Date: 2008-08-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100956211 Medline TA: J Microbiol Immunol Infect Country: China |
Other Details:
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Languages: eng Pagination: 41-7 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Pingtung Christian Hospital, Pingtung, Taiwan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antigens, Bacterial / urine* Child Child, Preschool Female Fever / diagnosis, drug therapy Humans Immunologic Tests / methods* Infant Infant, Newborn Male Pneumonia, Pneumococcal / diagnosis, drug therapy*, pathology Streptococcus pneumoniae / immunology*, isolation & purification Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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