Document Detail


Clinical application of the rapid pneumococcal urinary antigen test in the treatment of severe pneumonia in children.
MedLine Citation:
PMID:  18327425     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: To evaluate the efficacy of the pneumococcal urinary antigen test (PUAT) in severe pediatric pneumonia. METHODS: The study enrolled 245 pediatric patients with severe pneumonia. Patients were divided into four groups; groups 1 and 2 received PUAT, while groups 3 and 4 did not. Additionally, PUAT-positive group 1 patients were treated with penicillin, while PUAT-negative patients received ampicillin-sulbactam or cefuroxime. Group 2 patients were treated empirically without following the group 1 protocol. Group 3 patients were treated following the guideline of the Infectious Diseases Society of Taiwan (IDST), and group 4 patients were treated empirically without following the IDST guideline. Treatment was assessed by the duration of fever. RESULTS: Treatment was most effective for group 1 and least effective for group 4. Group 2 treatment was superior to group 3 treatment. Multivariate regression analysis of groups 1 and 2 revealed that the use of PUAT (groups 1 and 2) was associated with superior response in comparison with group 4. CONCLUSION: Application of PUAT and adequate antimicrobial treatments in the initial stage for pediatric patients with severe pneumonia resulted in improved outcome as assessed by shortening of the duration of fever.
Authors:
Huey-Fung Cheong; Luo-Ping Ger; Ming-Ting Wu; Chih-Pei Sun; Kai-Sheng Hsieh; Yung-Ching Liu; Ming-Fang Cheng
Related Documents :
23133715 - The clinical efficacy of decompressive craniectomy in patients with an internal carotid...
23890495 - Clinical and radiological results of radiolunate arthrodesis for rheumatoid arthritis: ...
10476745 - A comparison of chloramphenicol, trimethoprim-sulfamethoxazole, and doxycycline with do...
23262925 - Surgical staples compared with subcuticular suture for skin closure after cesarean deli...
21577295 - Recent advances in the management of distal ulcerative colitis.
9313535 - Benign prostatic hyperplasia in older men.
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi     Volume:  41     ISSN:  1684-1182     ISO Abbreviation:  J Microbiol Immunol Infect     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-10     Completed Date:  2008-08-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100956211     Medline TA:  J Microbiol Immunol Infect     Country:  China    
Other Details:
Languages:  eng     Pagination:  41-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Pingtung Christian Hospital, Pingtung, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Antigens, Bacterial / urine*
Child
Child, Preschool
Female
Fever / diagnosis,  drug therapy
Humans
Immunologic Tests / methods*
Infant
Infant, Newborn
Male
Pneumonia, Pneumococcal / diagnosis,  drug therapy*,  pathology
Streptococcus pneumoniae / immunology*,  isolation & purification
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antigens, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Low rate of nasopharyngeal carriage and high rate of ampicillin resistance for Haemophilus influenza...
Next Document:  Clinical features and prognostic factors in childhood pneumococcal meningitis.