Document Detail


Clinical application of interventional renal sympathetic denervation: recommendations of the Austrian Society of Hypertension 2012.
MedLine Citation:
PMID:  23184070     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Increased activity of the sympathetic nervous system plays a major role in the pathophysiology of primary arterial hypertension. Interventional renal sympathetic denervation (RSD) is a novel percutaneous treatment, decreasing sympathetic activity and consecutively blood pressure by ablating sympathetic nervous fibers located in the adventitia of the renal arteries. The procedure has been tested in several clinical trials in patients with resistant hypertension (defined as systolic office blood pressure > 160 mmHg-in diabetic patients > 150 mmHg-treated with ³ 3 antihypertensive drugs) and caused a meaningful blood pressure reduction, lasting for at least 3 years. So far, no major adverse events have been identified; however, data on the long-term consequences are lacking. The present position paper of the Austrian Society of Hypertension is aiming to assist in choosing possible indications for RSD in clinical routine, based on the available evidence in 2012.
Authors:
Thomas Weber; Robert Zweiker; Bruno Watschinger; Peter Grüner; Christian Koppelstätter; Mathias C Brandt; Jörg Horina; Helmut Brussee; Katharina Hohenstein; Thomas Lambert; Johann Auer; Uta C Hoppe
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-27
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  -     ISSN:  1613-7671     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Kardiologische Abteilung, Klinikum Wels-Grieskirchen, Grieskirchnerstrasse 42, 4600, Wels, Austria, thomas.weber@klinikum-wegr.at.
Vernacular Title:
Klinischer Einsatz der interventionellen renalen Sympathikusdenervierung - Empfehlungen der Österreichischen Gesellschaft für Hypertensiologie 2012.
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