Document Detail

Clinical application of electrocardiographic computer model.
MedLine Citation:
PMID:  2614315     Owner:  NLM     Status:  MEDLINE    
A three-dimensional computer model was developed to stimulate the ventricular depolarization and repolarization in a clinical setting. The ventricle is composed of approximately 50,000 units arranged in a cubic close-packed structure and the specialized conduction system is distributed so as to obtain the excitation sequence resembling normal ventricular depolarization. The normal distribution of action potential waveforms with the longest duration on the endocardium and the shortest on the epicardium is used in the model. The heart model is mounted in a homogeneous torso model, and the body surface potential distribution generated by the electric dipoles is calculated using the boundary element method. The QRST waveforms corresponding to the normal and some abnormal heart conditions, such as bundle branch block, myocardial infarction, apical hypertrophic cardiomyopathy, and Wolff-Parkinson-White syndrome, is obtained by assuming the abnormal area with altered electrical properties. Thus the three-dimensional computer model may provide further insight into the genesis of the clinical electrocardiogram.
K Harumi; H Tsunakawa; G Nishiyama; D Wei; G Yamada; Y Okamoto; T Musha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  22 Suppl     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-15     Completed Date:  1990-03-15     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  54-63     Citation Subset:  IM    
Nakano National Chest Hospital, Tokyo, Japan.
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MeSH Terms
Bundle-Branch Block / physiopathology
Cardiomyopathy, Hypertrophic / physiopathology
Computer Simulation*
Coronary Disease / physiopathology
Heart / physiology,  physiopathology
Models, Cardiovascular*
Myocardial Infarction / physiopathology
Signal Processing, Computer-Assisted
Tachycardia, Supraventricular / physiopathology
Wolff-Parkinson-White Syndrome / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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