Document Detail


Clinical and angiographic outcome in patients with in-stent restenosis and repeat target lesion revascularisation in small coronary arteries.
MedLine Citation:
PMID:  10956297     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the clinical and angiographic outcome in patients with in-stent restenosis in small coronary arteries and repeat target lesion revascularisation. DESIGN: Patients with in-stent restenosis in coronary arteries < or = 2.85 mm were eligible for the study and underwent target lesion revascularisation. Clinical and angiographic variables were assessed during a six month follow up period. RESULTS: 73 patients with 79 lesions were treated by percutaneous transluminal coronary angioplasty (47%), excimer laser angioplasty (25%), or restenting (28%). The mean (SD) reference diameter before target lesion revascularisation was 2.12 (0.5) mm. Procedural success was achieved in all cases, but 57% of the patients had restenosis after six months. The rate of further restenosis was higher with laser angioplasty (78%) than with restenting (47%) or balloon angioplasty alone (49%, p < 0.05). CONCLUSIONS: Treatment for in-stent restenosis in small coronary arteries is feasible and safe, with a second restenosis rate comparable to large coronary artery series. The strategy of target lesion revascularisation influences further in-stent restenosis, with an increased rate with laser angioplasty compared with restenting and repeat dilatation alone.
Authors:
C M Gross; J Krämer; O Weingärtner; F Uhlich; R Dietz; J Waigand
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  84     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-09-19     Completed Date:  2000-09-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  307-13     Citation Subset:  AIM; IM    
Affiliation:
Franz Volhard Clinic at the Max Delbrück Centre, Charité, Campus Berlin-Buch, Humboldt University, Berlin, Germany. Gross@fvk-berlin.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Analysis of Variance
Angioplasty, Balloon, Laser-Assisted*
Angioplasty, Transluminal, Percutaneous Coronary*
Chi-Square Distribution
Coronary Angiography
Coronary Disease / radiography,  therapy*
Evaluation Studies as Topic
Female
Humans
Male
Microcirculation
Middle Aged
Recurrence
Reoperation
Stents*
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