Document Detail

Clinical and angiographic outcome after coronary arterial stenting with the carbostent.
MedLine Citation:
PMID:  10758920     Owner:  NLM     Status:  MEDLINE    
The Carbostent is a new balloon-expandable, stainless steel, tubular stent with innovative multicellular design and unique turbastratic carbon coating (Carbofilm). This open nonrandomized 2-center study assesses the immediate and long-term clinical and angiographic outcomes after Carbostent implantation in patients with native coronary artery disease. The Carbostent was implanted in 112 patients with 132 de novo lesions. Most patients (55%) had unstable angina, and 38% of lesions were type B2-C. The mean lesion length was 12.5 +/- 7.0 mm, and 29% of lesions were > 15 mm in length. No stent deployment failure occurred, as well as acute or sub-acute stent thrombosis. The 6-month event-free survival was 84 +/- 4%. One patient with a stented right coronary artery and no restenosis at the angiographic follow-up died after 6 months of fatal infarction due to abrupt closure of a nontarget vessel. In-hospital non-Q-wave myocardial infarction occurred in 1 patient, and 11 patients had repeat target lesion revascularization (target lesion revascularization rate 10%). The 6-month angiographic follow-up was obtained in 108 patients (96%) (127 lesions). Angiographic restenosis rate was 11%. The loss index was 0.29 +/- 0.28. The results of this study indicate a potential benefit of Carbostent for the prevention of stent thrombosis and restenosis in these relatively high-risk patients. A larger trial is being planned to confirm these promising results.
D Antoniucci; A Bartorelli; R Valenti; P Montorsi; G M Santoro; F Fabbiocchi; L Bolognese; A Loaldi; M Trapani; D Trabattoni; G Moschi; S Galli
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  The American journal of cardiology     Volume:  85     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-04-21     Completed Date:  2000-04-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  821-5     Citation Subset:  AIM; IM    
The Division of Cardiology, Careggi Hospital, Florence, Italy.
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MeSH Terms
Angina, Unstable / radiography*,  therapy*
Angioplasty, Transluminal, Percutaneous Coronary*
Coated Materials, Biocompatible*
Coronary Angiography*
Disease-Free Survival
Middle Aged
Postoperative Period
Retrospective Studies
Treatment Outcome
Reg. No./Substance:
0/Coated Materials, Biocompatible; 7440-44-0/Carbon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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