Document Detail


Clinical analysis of necrotizing pneumonia in children: three-year experience in a single medical center.
MedLine Citation:
PMID:  14983656     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Necrotizing pneumonia (NP) is a rare but complex complication of lobar pneumonia in children. It is characterized by massive necrosis and liquification of lung tissues by the presence of multiple cavities rather than a solitary one. To evaluate the clinical features of NP, we enrolled 17 patients at Chang-Gung Memorial Hospital (Kaohsiung) from November 1999 to December 2002. The diagnosis of NP was based upon findings of chest computed tomography. There were six boys and 11 girls, ages ranging from 47 days to seven years. Streptococcus pneumoniae was the most common pathogen responsible for 9 cases in our study. Our patients remained febrile, even with the appropriate antibiotics administered, for a mean of 12.1 +/- 5.2 days and hospitalized for a mean of 22.7 +/- 7.0 days. The right lung was affected more than the left (12:7). On admission, laboratory data showed either leukocytosis, or normal leukocyte count, or leukopenia, but C-reactive protein was abnormally high (mean = 304.8 +/- 96.3 mg/L). Anemia and significant platelet count elevation developed at a mean period of 8.5 +/- 3.5 and 10.9 +/- 4.7 days after their hospitalization, respectively. Surgical intervention was performed in one case only in our series. Chest roentgenography took a mean of 60.3 +/- 15.6 days to resolve completely. Although the clinical course was prolonged, all patients with NP eventually recovered completely with no sequela.
Authors:
Kao-Chun Chen; Yu-Tsun Su; Wing-Lee Lin; Kuan-Chi Chiu; Chen-Kuang Niu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi     Volume:  44     ISSN:  1608-8115     ISO Abbreviation:  Acta Paediatr Taiwan     Publication Date:    2003 Nov-Dec
Date Detail:
Created Date:  2004-02-26     Completed Date:  2004-04-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100958202     Medline TA:  Acta Paediatr Taiwan     Country:  China (Republic: 1949- )    
Other Details:
Languages:  eng     Pagination:  343-8     Citation Subset:  IM    
Affiliation:
Division of Pediatric Pulmonology, Department of Pediatrics, Chang-Gung Memorial Hospital, Kaohsiung, 123, Ta-Pei Road, Niaosung, Kaohsiung, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Female
Humans
Infant
Male
Necrosis
Pneumonia, Pneumococcal / complications*

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