Document Detail

Clinical analysis of endophthalmitis after phacoemulsification.
MedLine Citation:
PMID:  18033327     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Most cases of exogenous endophthalmitis occur after intraocular surgery. Although phacoemulsification is quick and convenient, there are some risks involved, and infection is one of them. This study investigated the associated factors and methods of prevention and treatment of endophthalmitis after phacoemulsification. METHODS: A retrospective study was conducted of 84 497 phacoemulsification surgeries with intraocular lens implantation performed in the 10 branches of Mai Ge Ophthalmological Hospital, Tianjin, China, from 1993 to 2003. RESULTS: It was found that 14 patients suffered from postoperative endophthalmitis in 14 eyes. Among them there were 5 cases with rupturing of posterior lens capsule. Postoperative endophthalmitis was culture-positive in 7 cases. After treatment, 5 patients had a visual acuity of 2.0 or above, 4 patients experienced the perception of light or hand movement, and the remaining 5 patients had lost light perception (2 cases ultimately had optic atrophy, and ophthalmectomy was performed on 3 eyes). INTERPRETATION: Endophthalmitis after phacoemulsification surgery led to severe vision loss and blindness, although its incidence was low (0.02%) in this study. The most common organism isolated was Staphylococcus epidermidis, and rupturing of the posterior capsule was one of the main risk factors. Early diagnosis and treatment restored visual acuity in several cases, and improved phacoemulsification technique, including sterilization, helped reduce the incidence of endophthalmitis.
Xiangrong Cao; Aizhen Liu; Jing Zhang; Yang Li; Ying Jie; Weihua Liu; Yanjun Zeng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  42     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-06     Completed Date:  2008-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  844-8     Citation Subset:  IM    
Mai Ge Ophthalmological Hospital, Tianjin, China.
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MeSH Terms
Anti-Bacterial Agents / administration & dosage
Aqueous Humor / microbiology
Bacteria / isolation & purification
China / epidemiology
Endophthalmitis / epidemiology,  etiology*,  prevention & control*
Eye Infections, Bacterial / epidemiology,  etiology,  prevention & control
Lens Implantation, Intraocular
Middle Aged
Phacoemulsification / adverse effects*
Postoperative Complications*
Retrospective Studies
Risk Factors
Visual Acuity
Vitreous Body / microbiology
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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