Document Detail


Clinical Trials in Patients with Heart Failure and Preserved Left Ventricular Ejection Fraction.
MedLine Citation:
PMID:  24975913     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
There is no robust evidence that any treatment can modify the natural history of patients with heart failure and preserved left ventricular ejection fraction (HFpEF), although most agree that diuretics can control congestion and improve symptoms. HFpEF is often complicated by systemic and pulmonary hypertension, atrial fibrillation, obesity, chronic lung and kidney disease, lack of physical fitness, and old age that can complicate both diagnosis and management. Further trials should phenotype patients precisely and create better definitions of HFpEF based on biomarkers.
Authors:
John G F Cleland; Pierpaolo Pellicori; Riet Dierckx
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Publication Detail:
Type:  REVIEW    
Journal Detail:
Title:  Heart failure clinics     Volume:  10     ISSN:  1551-7136     ISO Abbreviation:  Heart Fail Clin     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-6-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231934     Medline TA:  Heart Fail Clin     Country:  -    
Other Details:
Languages:  ENG     Pagination:  511-523     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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