Document Detail


Clinical spectrum and prognostic factors of pediatric ventricular tachycardia.
MedLine Citation:
PMID:  20668351     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: There have been no studies on the clinical characteristics and prognostic factors of pediatric ventricular tachycardia (VT).
METHODS AND RESULTS: Eighty-one patients with pediatric VT were studied retrospectively at a single center. The median follow-up period was 6.0 years (0.7-23.5 years). Patients were categorized into 6 groups: idiopathic VT (IVT, n=37), catecholaminergic polymorphic VT (CPVT, n=10), congenital heart disease-associated VT (n=15), myocarditis-associated VT (n=8), cardiomyopathy-associated VT (CMP-VT, n=5) and miscellaneous. The age distribution of VT had 2 peaks (infant and teenager). VT with left bundle branch block configuration was more frequently nonsustained than VT with right bundle branch block configuration (61% vs 8%). Although 22% were asymptomatic, 38% experienced syncope or seizure and 16% had cardiac arrest. The overall mortality rate was 7.4%. The expected life span without cardiac arrest was <4 years in the CMP-VT group and the 10-year survival rate in CPVT patients was approximately 55%. Onset at infancy, monomorphic type and transcatheter/surgical ablation were related to the successful resolution of VT. Logistic regression analysis revealed that CPVT, CMP-VT, polymorphic VT and sustained VT were significantly correlated with death or cardiac arrest.
CONCLUSIONS: The clinical features and prognosis of pediatric VT differed with the VT type, clinical categories and onset age. Accurate diagnosis and proper treatment according to the clinical categories may improve the outcome.
Authors:
Mi-Kyoung Song; Jae-Suk Baek; Bo-Sang Kwon; Gi-Beom Kim; Eun-Jung Bae; Chung-Il Noh; Jung-Yun Choi
Publication Detail:
Type:  Journal Article     Date:  2010-07-27
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  74     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-31     Completed Date:  2010-12-22     Revised Date:  2011-02-18    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1951-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Age of Onset
Child
Child, Preschool
Death, Sudden, Cardiac
Female
Follow-Up Studies
Humans
Infant
Infant, Newborn
Male
Prognosis
Retrospective Studies
Tachycardia, Ventricular / classification*,  diagnosis*
Treatment Outcome
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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