Document Detail


Clinical screening and genetic testing.
MedLine Citation:
PMID:  20347791     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clinical screening is most effective in diseases in which the disease in its earliest form and may not have symptoms or signs but can be readily diagnosed with an inexpensive, noninvasive test. This article discusses the general principles of genetic disease architecture that can guide screening and diagnostic approaches for all of the cardiomyopathies and inherited diseases. It addresses how the genetic architecture of the trait guides, and how clinical characteristics of the disease influence, a clinical screening approach.
Authors:
Rahul C Deo; Calum A MacRae
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Heart failure clinics     Volume:  6     ISSN:  1551-7136     ISO Abbreviation:  Heart Fail Clin     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-07-23     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  101231934     Medline TA:  Heart Fail Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  231-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Cardiomyopathy, Dilated / diagnosis,  epidemiology,  genetics*
Cardiomyopathy, Hypertrophic / diagnosis,  epidemiology,  genetics*
Genetic Predisposition to Disease
Genetic Testing*
Genomics
Humans
Penetrance
Prevalence
Prognosis
United States / epidemiology
Grant Support
ID/Acronym/Agency:
R01 HL075431/HL/NHLBI NIH HHS; R01 HL075431-01A1/HL/NHLBI NIH HHS; T32 HL007208/HL/NHLBI NIH HHS; T32 HL007208-32/HL/NHLBI NIH HHS
Comments/Corrections

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