| Clinical response to 2 commonly used switch formulas occurs within 1 day. | |
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MedLine Citation:
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PMID: 18832532 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Very fussy or extremely fussy infants were randomized to receive: soy-based formula (Soy: n = 82) or a partially hydrolyzed cow's milk protein (CMP), low-lactose formula (PHF: n = 77) in a multicenter, double-blind, randomized, parallel, prospective 28-day feeding trial. Body weight and infant formula tolerance were reported. Adverse events were recorded throughout the study. A significant reduction in mean scores of fussiness, gas, spit-up, and crying compared with baseline measures was observed in infants who received either Soy or PHF within 1 day of formula intake; improvement in symptoms was sustained by study end. Stool consistency remained constant through day 28 in the PHF group, whereas stools in the Soy group became more firm by day 2 and did not return to prestudy consistency. PHF, with a protein profile patterned more closely on human breast milk, improved symptoms of formula intolerance as well as soy-based formula. |
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Authors:
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Carol Lynn Berseth; William H Johnston; Suzanne I Stolz; Cheryl L Harris; Susan Hazels Mitmesser |
Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial Date: 2008-10-02 |
Journal Detail:
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Title: Clinical pediatrics Volume: 48 ISSN: 0009-9228 ISO Abbreviation: Clin Pediatr (Phila) Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2008-12-05 Completed Date: 2009-02-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372606 Medline TA: Clin Pediatr (Phila) Country: United States |
Other Details:
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Languages: eng Pagination: 58-65 Citation Subset: AIM; IM |
Affiliation:
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Mead Johnson Nutritionals, Evansville, Indiana 47721, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Double-Blind Method Feces Humans Infant Infant Behavior Infant Formula* Lactose Milk Proteins Prospective Studies Soy Milk |
| Chemical | |
Reg. No./Substance:
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0/Milk Proteins; 63-42-3/Lactose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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