Document Detail


Clinical predictors and management of hemorrhagic transformation.
MedLine Citation:
PMID:  23325069     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Hemorrhagic Transformation (HT) has been well recognized as a common cause of hemorrhage in ischemic stroke patients. Though this complication may occur independently, it has been particularly dreaded in the post rTPA patient and thus has been the focus for analysis of multiple thrombolytic trials. This review examines the effect of different clinical predictors for hemorrhagic transformation and summarizes pertinent clinical trials, with a focus on the rational for design of future studies. Although currently there are no official guidelines for the acute management of HT per se, based upon review of the literature regarding pertinent clinical predictors herein, an innovative approach for the acute management of the HT patient is proposed.
Authors:
Raphaella E Weiser; Kevin N Sheth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current treatment options in neurology     Volume:  15     ISSN:  1092-8480     ISO Abbreviation:  Curr Treat Options Neurol     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-29     Completed Date:  2013-04-01     Revised Date:  2013-07-25    
Medline Journal Info:
Nlm Unique ID:  9815940     Medline TA:  Curr Treat Options Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  125-49     Citation Subset:  -    
Affiliation:
Department of Neurology, University of Maryland Medical Center, 22 South Green Street, Baltimore, MD, 21201, USA, rweiser@umaryland.edu.
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