| A clinical picture of guillain-barre syndrome in children in the United States. | |
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MedLine Citation:
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PMID: 20823034 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The authors describe the demographics, clinical presentation, investigation, treatment, and outcomes of pediatric patients with Guillain-Barré syndrome. They identified 35 pediatric patients with Guillain-Barré syndrome presenting to a tertiary academic center over a 20-year period. The most common presenting symptoms were paresthesias (54%), weakness (49%), and myalgias (49%). Sensation was affected in 54% of patients, and hyporeflexia or areflexia was present in 94% of patients. Cranial nerve dysfunction (46%) and autonomic involvement (eg, changes in blood pressure, pulse, bowel/bladder control, or priapism; 46%) were also common. Autonomic dysfunction, cranial nerve involvement, and albuminocytological dissociation were significantly associated with a decreased time to nadir, the point when symptoms peaked (P = .015, .007, and .005, respectively). Although not statistically significant, treatment with plasmapheresis had a better success rate than intravenous immunoglobulin. The authors' results will help to further delineate the clinical picture of Guillain-Barré syndrome in children and refine treatment strategies. |
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Authors:
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Caitlin W Hicks; Benjamin Kay; Sarah E Worley; Manikum Moodley |
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Publication Detail:
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Type: Journal Article Date: 2010-09-07 |
Journal Detail:
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Title: Journal of child neurology Volume: 25 ISSN: 1708-8283 ISO Abbreviation: J. Child Neurol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 1504-10 Citation Subset: IM |
Affiliation:
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Cleveland Clinic, Cleveland, OH, Cleveland Clinic Lerner College of Medicine, Cleveland, OH. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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