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Clinical Periodontal and Microbiologic Parameters in Patients with Rheumatoid Arthritis.
MedLine Citation:
PMID:  21405936     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: A limited number of studies suggest the prevalence of periodontal pathogens in patients with rheumatoid arthritis (RA); however, results are inconsistent. The aim of this study was to investigate clinical periodontal and microbiologic parameters in patients with RA. Methods: 66 patients with RA aged 49.5±8.4 years participated in the study. The periodontal situation was assessed with the periodontal screening index (PSR(®)/PSI); allocated to: healthy, gingivitis (PSR(®)/PSI score 0-2, max. one sextant score 3), moderate (more than one sextant PSR(®)/PSI score 3, max. one sextant score 4) or severe periodontitis (more than one sextant PSR(®)/PSI score 4). Pool samples were taken for microbiological (PCR-) analysis(§) for the presence of 11 periodontal pathogens. Statistical analysis: non-parametric analysis of covariance. Results: No patient was periodontal healthy; 24 patients were classified as having gingivitis; 18 patients had a moderate and 23 severe periodontitis; one patient was toothless. For most patients, Fusobacterium nucleatum (98%), Eikanella corrodens (91%) and Peptostreptococcus micros (88%) were above the detection threshold; strong periodontal pathogens were less frequently detected: Aggregatibacter actinomycetemcomitans (16%), Porphyromonas gingivalis (58%) and Tannerella forsythia (78%). Statistical analysis showed no significant influence of rheumatic factor (p=0.33) on periodontal situation and on microbiologic parameters (p>0.05).Only smoking showed a significant influence (p=0.0004) on the periodontal situation and in the case of Ec (p=0.02). Conclusion: Most of patients with rheumatoid arthritis investigated showed a moderate to severe periodontitis as well as the presence of periodontal pathogens. No association was found between rheumatic factor on periodontal situation and microbiologic parameters.
Authors:
Dirk Ziebolz; Sven O Pabel; Katharina Lange; Berndt Krohn-Grimberghe; Else Hornecker; Rainer F Mausberg
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-15
Journal Detail:
Title:  Journal of periodontology     Volume:  -     ISSN:  1943-3670     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center Goettingen, Germany.
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