Document Detail


Clinical pathological characteristics and management of acute respiratory distress syndrome resulting from influenza A (H1N1) virus.
MedLine Citation:
PMID:  20622733     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Young adults, especially pregnant woman and patients with pre-existing medical conditions, appear to be at risk for the development of severe acute respiratory distress syndrome (ARDS) from influenza A (H1N1) infection, leading to critical hypoxemia. This may require high ventilator settings, the use of nonconventional modes, and extracorporeal membrane oxygenation in some cases. This severe ARDS may be related to prolonged and virulent viral infection, inducing ongoing aberrant immune responses and leading to extensive lung damage. Duration of antiviral therapy, the timing of steroid introduction, and moving away from standard ventilation techniques in ARDS may be key points in disease management.
Authors:
Samer Homsi; Natasa Milojkovic; Yamen Homsi
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  103     ISSN:  1541-8243     ISO Abbreviation:  South. Med. J.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-03     Completed Date:  2010-08-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  786-90; quiz 791-2     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Division of Pulmonary and Critical Care, St. Edwards Mercy Medical Center, Fort Smith, AR 72903, USA. homssx@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiviral Agents / therapeutic use
Extracorporeal Membrane Oxygenation
Female
Humans
Influenza A Virus, H1N1 Subtype*
Influenza, Human / complications*,  diagnosis,  drug therapy,  therapy
Male
Pregnancy
Respiratory Distress Syndrome, Adult / etiology,  therapy*
Risk Factors
Chemical
Reg. No./Substance:
0/Antiviral Agents
Comments/Corrections
Comment In:
South Med J. 2010 Aug;103(8):727-8   [PMID:  20622735 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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