Document Detail


Clinical outcomes comparing parenteral and nasogastric tube nutrition after laryngeal and pharyngeal cancer surgery.
MedLine Citation:
PMID:  19255706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nasogastric tube-assisted enteral feeding and parenteral feeding are utilized for nutritional support after major surgery. Although these nutritional supports have been compared before, there have been no comparative trials following surgery for laryngeal and pharyngeal cancer. In this study, 81 patients were randomized to total parenteral nutrition (TPN) or nasogastric tube nutrition (NGTN) after laryngopharyngeal cancer surgery. The two groups were well-matched demographically and clinically. Clinical outcomes such as time of commencement of oral feeding and hospital stay and complications such as fistula were similar in both groups. One case in the TPN group had catheter-related sepsis, whereas aspiration pneumonia occurred in four cases (9.8%) in the NGTN group. The daily cost of NGTN was $11.81 cheaper than that of TPN. Subjective symptoms of nasal and pharyngeal discomfort and scores on subjective swallowing were more severe in the NGTN group within the first postoperative week but became similar thereafter. Although there was no difference in objective postoperative outcomes between both groups, these results imply that each method had particular advantages and disadvantages. Nutritional support after laryngopharyngeal cancer surgery should be determined after full consideration of each patient's conditions and surgical details along with economics.
Authors:
Junsun Ryu; Byung-Ho Nam; Yuh-Seog Jung
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-03-03
Journal Detail:
Title:  Dysphagia     Volume:  24     ISSN:  1432-0460     ISO Abbreviation:  Dysphagia     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-21     Completed Date:  2010-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610856     Medline TA:  Dysphagia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  378-86     Citation Subset:  IM    
Affiliation:
Head and Neck Oncology Clinic, Department of Otolaryngology, National Cancer Center, Goyang, Gyeonggi-do, Korea.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Costs and Cost Analysis
Deglutition / physiology
Deglutition Disorders / etiology,  physiopathology
Female
Humans
Intubation, Gastrointestinal* / adverse effects,  economics
Laryngeal Neoplasms / surgery*
Male
Middle Aged
Parenteral Nutrition, Total* / adverse effects,  economics
Pharyngeal Neoplasms / surgery*
Postoperative Care / methods
Postoperative Complications / etiology
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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