Document Detail

Clinical Heterogeneity of Desmoplastic Infantile Ganglioglioma: A Case Series and Literature Review.
MedLine Citation:
PMID:  22735886     Owner:  NLM     Status:  Publisher    
Desmoplastic infantile gangliogliomas (DIG) are intracranial tumors described in 1987 as benign lesions of infancy. A literature review and the clinical course of 3 patients reported herein suggest that the initial description should be amended. Nearly 23% of DIG cases occur in children older than 24 months. Approximately 40% of DIG cases require additional medical, radiation, and/or further surgical intervention, and 15% of infants and children develop leptomeningeal spread or die from DIG. Such adverse outcomes, combined with the recognition that DIG represents a heterogeneous disease, underscore the need for an expanded biological and molecular investigation.
Trent R Hummel; Lili Miles; Francesco T Mangano; Blaise V Jones; James I Geller
Related Documents :
22735886 - Clinical heterogeneity of desmoplastic infantile ganglioglioma: a case series and liter...
22678496 - Anatomic study of the lamina terminalis: neurosurgical relevance in approaching lesions...
8187666 - Erotic delusions: a case report.
8936606 - Schizophrenia, schizotypal and delusional disorders (f2). results from the icd-10 field...
3827546 - Malignant paraganglioma of the thyroid gland.
20446076 - Bactrian ("double hump") acetaminophen pharmacokinetics: a case series and review of th...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-25
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  -     ISSN:  1536-3678     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
*Cancer and Blood Diseases Institute, Division of Oncology †Division of Pathology and Laboratory Medicine ‡Department of Pediatric Neurological Surgery §Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati OH.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vincristine, Irinotecan, and Temozolomide for Treatment of Relapsed Alveolar Rhabdomyosarcoma.
Next Document:  Immune Function in Newly Diagnosed Children With Malignancy.