| Clinical and genetic characteristics of meconium ileus in newborns with and without cystic fibrosis. | |
| | |
MedLine Citation:
|
PMID: 20386322 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
The present study compares the clinical presentation and diagnostic features of meconium ileus (MI) in newborns with and without cystic fibrosis (CF). A retrospective study of 43 patients treated in the Pediatric Surgical Center of Amsterdam was performed. Twenty-three of the patients (53.5%) were diagnosed as having CF. Complex MI was significantly more frequent in patients without CF, and these patients had lower gestational ages and birth weights than patients with CF. All of the patients with complex MI had homozygous DF508 mutations, whereas the patients with simple MI also had other mutations. None of the patients with other mutations had complex MI. Therefore, we conclude that the clinical entity of MI represents a spectrum of underlying pathologies. |
| | |
Authors:
|
R R Gorter; A Karimi; C Sleeboom; C M F Kneepkens; H A Heij |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Journal of pediatric gastroenterology and nutrition Volume: 50 ISSN: 1536-4801 ISO Abbreviation: J. Pediatr. Gastroenterol. Nutr. Publication Date: 2010 May |
Date Detail:
|
Created Date: 2010-04-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8211545 Medline TA: J Pediatr Gastroenterol Nutr Country: United States |
Other Details:
|
Languages: eng Pagination: 569-72 Citation Subset: IM |
Affiliation:
|
Pediatric Surgical Center of Amsterdam, Emma Children's Hospital and VU University Medical Center, Amsterdam, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effectiveness of infliximab in Brazilian children and adolescents with Crohn disease and ulcerative ...
Next Document: Feeding after percutaneous endoscopic gastrostomy in children: early feeding trial.