Document Detail


Clinco-epidemiologic study of cutaneous leishmaniasis in Bikaner, Rajasthan, India.
MedLine Citation:
PMID:  23716414     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cutaneous leishmaniasis is endemic to the Thar Desert of Rajasthan, Bikaner, India. The present study describes clinico-epidemiologcial data of all cases of cutaneous leishmaniasis CL in this region during 2001-2011. A total of 1,379 patients with 2,730 lesions were reported during the study period. Ages of patients ranged from 3 months to 86 years, and there was a predominance of infections in males. Most patients were from urban areas and lower middle socioeconomic groups. Lesions were dry, ulcerated nodules or plaques of different sizes commonly over face and upper limb. Skin smears were positive for parasites in 958 (69.5%) patients, and the remaining 45.8% (193 of 421) patients were positive by skin biopsy. Histopathologic analysis of the skin showed mixed granulomas consisting of macrophages, lymphocytes, epitheloid, and plasma cells. Species identification was conducted for 45 randomly selected patients by polymerase chain reaction, the infective species was Leishmania tropica. Most patients were treated with intra-lesional injections of sodium stibogluconate.
Authors:
Naushin Aara; Kanika Khandelwal; Ram A Bumb; Rajesh D Mehta; Bhikam C Ghiya; Renu Jakhar; Claire Dodd; Poonam Salotra; Abhay R Satoskar
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Publication Detail:
Type:  Journal Article     Date:  2013-05-28
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  89     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-07-11     Completed Date:  2013-09-16     Revised Date:  2014-07-13    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Humans
India / epidemiology
Infant
Leishmaniasis, Cutaneous / drug therapy,  epidemiology*,  pathology
Male
Middle Aged
Prevalence
Risk Factors
Sex Factors
Skin / pathology
Socioeconomic Factors
Young Adult
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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