Document Detail


Clevidipine (the Medicines Company).
MedLine Citation:
PMID:  12431021     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Medicines Company (under license from AstraZeneca) is developing clevidipine, a short-acting dihydropyridine calcium antagonist, for the potential treatment of peri-operative hypertension. By 1997, the compound was undergoing phase II clinical evaluation by the original developer, AstraZeneca. By March 2002, The Medicines Company was conducting phase III clinical trials.
Authors:
Hongwei Zhang
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in investigational drugs (London, England : 2000)     Volume:  3     ISSN:  1472-4472     ISO Abbreviation:  Curr Opin Investig Drugs     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-11-14     Completed Date:  2003-04-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100965718     Medline TA:  Curr Opin Investig Drugs     Country:  England    
Other Details:
Languages:  eng     Pagination:  1474-8     Citation Subset:  IM    
Affiliation:
Department of General Surgery, The Second Affiliated Hospital of Zhong Shan University, Guangzhou, PR China. hongweizhang67@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Antihypertensive Agents / pharmacology*
Calcium Channel Blockers / pharmacology*
Clinical Trials as Topic
Humans
Pyridines / metabolism,  pharmacology*,  therapeutic use
Structure-Activity Relationship
Chemical
Reg. No./Substance:
0/Antihypertensive Agents; 0/Calcium Channel Blockers; 0/Pyridines; 0/clevidipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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