| The Cleveland NIAAA prospective alcohol-in-pregnancy study: the first year. | |
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MedLine Citation:
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PMID: 7254465 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Data from 2,913 antepartum gravidas screened for alcohol problems during the first year of a large prospective study designed to relate antenatal drinking behavior to infant outcome have been analyzed. The Michigan Alcoholism Screening Test (MAST) appears to separate two populations of pregnant patients. Differences between positive and negative MAST responders indicate variables, such as ethnicity, previous pregnancies, nutrition and cigarette smoking, which will require control when infant outcome data are evaluated. Positive MAST responders were found to be more likely to drink alcohol, to drink greater volumes and to drink more frequently than matched negative responders. They obtained a smaller proportion of their alcohol intake from wine and were more likely to drink a combination of beer, wine and/or liquor than the negative responders. The positive responders significantly decreased their alcohol intake as pregnancy progressed, while negative responders did not, suggesting the possibility that abstinence oriented therapy may be helpful. Problems with quantitating alcohol intake by humans and strategies for separating chronic and acute alcohol effects are discussed. |
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Authors:
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R J Sokol; S I Miller; S Debanne; N Golden; G Collins; J Kaplan; S Martier |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Neurobehavioral toxicology and teratology Volume: 3 ISSN: 0275-1380 ISO Abbreviation: Neurobehav Toxicol Teratol Publication Date: 1981 |
Date Detail:
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Created Date: 1981-09-15 Completed Date: 1981-09-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8104162 Medline TA: Neurobehav Toxicol Teratol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 203-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcohol Drinking Alcoholic Beverages / adverse effects* Alcoholism / complications, prevention & control Female Fetus / drug effects* Health Education Humans Nutrition Disorders / complications Ohio Pregnancy Pregnancy Complications Prospective Studies |
| Grant Support | |
ID/Acronym/Agency:
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1P50 HD 11089/HD/NICHD NIH HHS; 5M01-RR00210/RR/NCRR NIH HHS; AA03282/AA/NIAAA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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