Document Detail


Clenbuterol induced changes in cholesterol and triglyceride levels of gastrocnemius, pectoralis and heart of rat under work induced stress.
MedLine Citation:
PMID:  15320501     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Work induced stress led to decreased cholesterol and fluctuating triglyceride levels in gastrocnemius and pectoralis muscles in rats. But the drug (clenbuterol, 2 mg kg(-1) day(-1)) treatment increased cholesterol and triglyceride levels in both the muscles. However, heart showed decreased cholesterol and increased triglyceride level in the animals under work stress, but at the same time drug treatment led to a significant increase in levels of the two lipid fractions, inferring towards deleterious effect of the drug on heart.
Authors:
Sushma Sharma; Asha Garg
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  41     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2004-08-23     Completed Date:  2004-09-23     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  India    
Other Details:
Languages:  eng     Pagination:  1452-5     Citation Subset:  IM    
Affiliation:
Department of Bio-Sciences, Himachal Pradesh University, Shimla 171 005, India. sushma_bio_sci@rediffmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Cholesterol / metabolism*
Clenbuterol / pharmacology*
Male
Muscle, Skeletal / drug effects*,  metabolism
Myocardium / metabolism*
Physical Conditioning, Animal
Rats
Rats, Wistar
Stress, Physiological / metabolism*
Triglycerides / metabolism*
Chemical
Reg. No./Substance:
0/Triglycerides; 37148-27-9/Clenbuterol; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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