Document Detail


Cleavage in vitro following destruction of some blastomeres in the marsupial Antechinus stuartii (Macleay).
MedLine Citation:
PMID:  3723068     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of destruction of some blastomeres on subsequent cleavage in vitro was investigated in the marsupial Antechinus stuartii. Blastomeres were killed by puncturing with a fine glass needle. The positions of the punctured and surviving blastomeres were recorded with respect to the yolk mass and defects on the shell membrane. Blastomeres were punctured in 2-cell, 4-cell, 14-cell, 16-cell and 22-cell embryos. Subsequent development of the embryos was followed in vitro. Embryos developed at a normal rate after destruction of some blastomeres. Puncturing of the shell, mucoid layer and zona pellucida, without damage to blastomeres, did not affect subsequent development. The embryos developed in accordance with the proportion of surviving blastomeres. Embryos with half of the blastomeres surviving developed as embryos with half the zona pellucida lined by blastomeres. Embryos with 1/4 of the blastomeres destroyed developed as 3/4 embryos. It is not known, without transfer into surrogate mothers, whether these fractional embryos were capable of developing into complete embryos.
Authors:
L Selwood
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of embryology and experimental morphology     Volume:  92     ISSN:  0022-0752     ISO Abbreviation:  J Embryol Exp Morphol     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-07-25     Completed Date:  1986-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7906439     Medline TA:  J Embryol Exp Morphol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  71-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blastomeres / physiology*
Cell Division
Cell Survival
Cells, Cultured
Cleavage Stage, Ovum / cytology,  physiology*
Marsupialia / embryology*
Time Factors
Zona Pellucida / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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