Document Detail

Clearance of indocyanine green as an index of liver function during cyclopropane anaesthesia and induced hypotension.
MedLine Citation:
PMID:  1259889     Owner:  NLM     Status:  MEDLINE    
The rate of decrease in the plasma concentration of indocyanine green (ICG) following a bolus i.v. injection has been studied in two groups of patients before and during anaesthesia. In eight patients anaesthetized with nitrous oxide and oxygen, and who received a neuromuscular blocking drug, induction of anaesthesia was not associated with a significant change in ICG half-life (from 4.59 to 3.85 min) but the subsequent administration of cyclopropane was associated with a statistically significant increase to 5.61 min. In a second group of anaesthetized patients, breathing spontaneously a mixture of oxygen, nitrous oxide and halothane, the induction of arterial hypotension with either lumbar extradural block or sodium nitroprusside was not associated with significant changes in ICG half-life.
A R Abdel Salam; G B Drummond; H W Bauld; D B Scott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  48     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  231-8     Citation Subset:  IM    
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MeSH Terms
Anesthesia, Epidural
Anesthesia, Inhalation*
Blood Pressure
Heart Rate
Hypotension, Controlled*
Indocyanine Green / diagnostic use*,  metabolism
Liver / metabolism*
Liver Function Tests
Middle Aged
Reg. No./Substance:
0/Cyclopropanes; 15078-28-1/Nitroprusside; 3599-32-4/Indocyanine Green

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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