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Clear cell renal cell carcinoma with osseous metaplasia: a case report.
MedLine Citation:
PMID:  21333055     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
INTRODUCTION: Osseous metaplasia is a rare histologic feature not often associated with renal cell carcinoma; there are only 14 reported cases and just four associated with the clear cell variant. We report the case of a 48-year-old female who presented with diffuse abdominal pain.
MATERIALS AND METHODS: We reviewed the case of woman who underwent a robotic assisted partial nephrectomy for an enhancing renal mass. Histologic analyses and immunostains were reviewed by multiple pathologists.
RESULTS: CT imaging revealed a 1.8 cm irregular enhancing exophytic mass with calcifications. The patient subsequently underwent robotic assisted laparoscopic partial nephrectomy. The final pathologic diagnosis was clear cell carcinoma with metaplastic bone formation.
CONCLUSION: While the prognostic significance of bone metaplasia occurrence in renal cell carcinoma is controversial, such that can safely be managed with partial nephrectomy.
Authors:
Robert J Hartman; Brian T Helfand; Daniel P Dalton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Canadian journal of urology     Volume:  18     ISSN:  1195-9479     ISO Abbreviation:  Can J Urol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9515842     Medline TA:  Can J Urol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  5564-7     Citation Subset:  IM    
Affiliation:
Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
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