Document Detail

Clear cell odontogenic carcinoma.
MedLine Citation:
PMID:  11854070     Owner:  NLM     Status:  MEDLINE    
Clear cell tumours, in the head and neck region, are usually derived from salivary or odontogenic tissues, or may be metastatic. A few clear cells may be present in odontogenic cysts, while, odontogenic neoplasms composed predominantly of clear cells are quite rare. They include calcifying epithelial odontogenic tumours (CEOT), ameloblastoma and odontogenic carcinoma. Clear cell odontogenic tumour (CCOT) has been classified in the last WHO classification as a benign tumour, but it is now recognized as a more sinister lesion and current opinion is that CCOT should be designated as a carcinoma. These tumours are characterized by aggressive growth, recurrences, and metastatic disease. A recent review of the literature has yielded 30 cases of tumours with similar characteristics. These tumours have a peak incidence in the 5th-7th decades, with a female predilection. The anterior portions of the jaws, especially the mandible, are most frequently affected. The aggressive potential of these neoplasms is well documented by the extensive invasion of adjacent tissues, multiple recurrences and regional or distant metastases.
G Iezzi; C Rubini; M Fioroni; A Piattelli
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Oral oncology     Volume:  38     ISSN:  1368-8375     ISO Abbreviation:  Oral Oncol.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-20     Completed Date:  2002-04-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9709118     Medline TA:  Oral Oncol     Country:  England    
Other Details:
Languages:  eng     Pagination:  209-13     Citation Subset:  IM    
Dental School, University of Chieti, Italy.
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MeSH Terms
Adenocarcinoma, Clear Cell / chemistry,  pathology*
Follow-Up Studies
Keratins / analysis
Maxillary Neoplasms / chemistry,  pathology*
Middle Aged
Neoplasm Proteins / analysis
Odontogenic Tumors / chemistry,  pathology*
Reg. No./Substance:
0/Neoplasm Proteins; 68238-35-7/Keratins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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