| Clean-up and determination of sodium valproate in serum by high-performance liquid chromatography with fluorimetric detection. | |
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MedLine Citation:
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PMID: 1886916 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A method is reported for the determination of the anticonvulsant sodium valproate in serum by fluorimetric detection. HPLC is performed on a reversed-phase column with a mobile phase of acetonitrile/water (65:35, v/v) with cyclohexane carboxylic acid as an internal standard. Samples were derivatized with 4-bromomethyl-7-methoxycoumarin and the optimized conditions are reported. |
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Authors:
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E Bousquet; S Tirendi; N A Santagati; M Salvo; P Moncada Paterno Castello |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Die Pharmazie Volume: 46 ISSN: 0031-7144 ISO Abbreviation: Pharmazie Publication Date: 1991 Apr |
Date Detail:
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Created Date: 1991-10-07 Completed Date: 1991-10-07 Revised Date: 2007-01-29 |
Medline Journal Info:
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Nlm Unique ID: 9800766 Medline TA: Pharmazie Country: GERMANY |
Other Details:
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Languages: eng Pagination: 257-8 Citation Subset: IM |
Affiliation:
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Istituto di Chimica Farmaceutica e Tossicologica, Facoltá di Farmacia, Università di Catania, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromatography, High Pressure Liquid Humans Indicators and Reagents Spectrometry, Fluorescence Valproic Acid / blood* |
| Chemical | |
Reg. No./Substance:
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0/Indicators and Reagents; 99-66-1/Valproic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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