Document Detail


Classification of trigeminal neuralgia: clinical, therapeutic, and prognostic implications in a series of 144 patients undergoing microvascular decompression.
MedLine Citation:
PMID:  19392593     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECT: Trigeminal neuralgia (TN) presents a diagnostic challenge because of the variety of symptoms, findings during microvascular decompression (MVD), and postsurgical outcomes observed among patients who suffer from this disorder. Recently, a new paradigm for classification of TN was proposed, based on the quality of pain. This study represents the first clinical analysis of this paradigm. METHODS: The authors analyzed 144 consecutive cases involving patients who underwent MVD for TN. Preoperative symptoms were classified into 1 of 2 categories based on the preponderance of shocklike (Type 1 TN) or constant (Type 2 TN) pain. Analysis of clinical characteristics, neurovascular pathology, and postoperative outcome was performed. RESULTS: Compared with Type 2 TN, Type 1 TN patients were older, were more likely to have right-sided symptoms, and reported a shorter duration of symptoms prior to evaluation. Previous treatment by percutaneous or radiosurgical procedures was not a predictor of symptoms, surgical findings, or outcome (p = 0.48). Type 1 TN was significantly more likely to be associated with arterial compression. Venous or no compression was more common among Type 2 TN patients (p < 0.01). Type 1 TN patients were also more likely to be pain-free immediately after surgery, and less likely to have a recurrence of pain within 2 years (p < 0.05). Although a subset of patients progressed from Type 1 to Type 2 TN over time, their pathological and prognostic profiles nevertheless resembled those of Type 1 TN. CONCLUSIONS: Type 1 and Type 2 TN represent distinct clinical, pathological, and prognostic entities. Classification of patients according to this paradigm should be helpful to determine how best to treat patients with this disorder.
Authors:
Jonathan P Miller; Feridun Acar; Kim J Burchiel
Related Documents :
20737143 - Long-term outcome in patients treated for benign dural arteriovenous fistulas of the po...
19834373 - Delayed cyst formation after gamma knife radiosurgery for brain metastases.
20358153 - The risk factors for mortality in elderly patients with hip fractures: postoperative on...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  111     ISSN:  1933-0693     ISO Abbreviation:  J. Neurosurg.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-02     Completed Date:  2010-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1231-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Arteries / surgery
Decompression, Surgical
Disease Progression
Female
Humans
Male
Microvessels / surgery*
Middle Aged
Pain / surgery
Prognosis
Recurrence
Retrospective Studies
Treatment Outcome
Trigeminal Neuralgia / diagnosis*,  surgery*
Veins / surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Feasibility of ventricular expansion postmortem: a novel laboratory model for neurosurgical training...
Next Document:  Radiosurgery for intracranial hemangiopericytomas: outcomes after initial and repeat Gamma Knife sur...