Document Detail

Classification of malabsorption syndromes.
MedLine Citation:
PMID:  18431059     Owner:  NLM     Status:  MEDLINE    
Malabsorption syndrome is usually defined as the complex of symptoms secondary to maldigestion and/or malabsorption, realizing when the extension of the disease exceeds the ability of intestine compensation. Several conditions have been recognized as being responsible for this syndrome. Up to now, different criteria have been used to order them, but a definitive classification is still not available because of the complexity of the absorption process, the involvement of different organs and structures, and the coexistence of different mechanisms in some diseases causing malabsorption. We propose a new classification of diseases causing malabsorption syndrome according to the responsible etiopathogenetic mechanisms: (a) alteration of digestive processes; (b) alteration of uptake and transport caused by damage or reduction of absorption surface, and (c) miscellaneous. A comment about the mechanisms responsible for malabsorption is given for all the cited diseases.
Massimo Montalto; Luca Santoro; Ferruccio D'Onofrio; Valentina Curigliano; Dina Visca; Antonella Gallo; Giovanni Cammarota; Antonio Gasbarrini; Giovanni Gasbarrini
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-04-21
Journal Detail:
Title:  Digestive diseases (Basel, Switzerland)     Volume:  26     ISSN:  1421-9875     ISO Abbreviation:  Dig Dis     Publication Date:  2008  
Date Detail:
Created Date:  2008-04-23     Completed Date:  2008-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701186     Medline TA:  Dig Dis     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  104-11     Citation Subset:  IM    
Copyright Information:
2008 S. Karger AG, Basel.
Institute of Internal Medicine, Catholic University, Rome, Italy.
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MeSH Terms
Digestion / physiology
Intestinal Absorption / physiology
Malabsorption Syndromes / classification*,  physiopathology

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