Document Detail

Classification and grading of squamous cell carcinoma of the cervix.
MedLine Citation:
PMID:  8756019     Owner:  NLM     Status:  MEDLINE    
Two hundred and twenty three cases of squamous cell carcinoma of the cervix were classified according to their resemblance to cells in any of the layers in the ectocervix and a grade of low and high malignancy was also given to each case. Forty cases were classified as basal, 59 as prickle, 115 as intermediate and nine as superficial cell types. Ninety cases were high grade (seven basal, 14 prickle, 63 intermediate and six superficial) and 133 were low grades (33 basal, 45 prickle, 52 intermediate, three superficial). This study shows that the intermediate cell type is the commonest and are usually high grade tumours. The findings also support the idea that squamous cell carcinoma of the cervix may arise from any of the normal layers in ectocervix and suggests that squamous cell carcinoma of the cervix is not a single disease entity, but heterogenous group of tumours like the non-Hodgkin's B cell or T cell lymphomas. Further study is needed to correlate the cytokeratin subtypes and clinical features of each histological type.
M Odida; R Schmauz
Related Documents :
12429789 - Immunohistochemical comparison of p16 expression in actinic keratoses and squamous cell...
15896829 - Synchronous invasive squamous cell carcinoma and clear cell adenocarcinoma of the uteri...
3402219 - Gastric squamous cell carcinoma and fascioliasis in a llama.
15167969 - Human neutrophil defensins and secretory leukocyte proteinase inhibitor in squamous met...
6177089 - Intracellular keratins in normal and pathological bronchial mucosa. immunocytochemical ...
2373779 - A case of secondary cutaneous amyloidosis: epidermal keratinocytes produce amyloid in t...
14703799 - Sensitization of u937 cells to heat shock by oxalomalate, a competitive inhibitor of na...
7840249 - Adh-evoked [cl-]i-dependent transient in whole cell current of distal nephron cell line...
289439 - Isolation of thymidine-resistant cells from a thymidine-sensitive acute lymphoblastic l...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  East African medical journal     Volume:  73     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-09-26     Completed Date:  1996-09-26     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  S9-10     Citation Subset:  IM    
Department of Pathology, Makerere University Medical School, Kampala, Uganda.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Carcinoma, Squamous Cell / classification*,  etiology,  pathology*
Neoplasm Staging / methods
Reproducibility of Results
Uterine Cervical Neoplasms / classification*,  etiology,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Disruption of hemoglobin oxygen transport does not impact oxygen-dependent physiological processes i...
Next Document:  Effect of protein deficient cassava diet on Cercopithecus aethiops hearts and its possible role in t...