Document Detail


Classification and grading of squamous cell carcinoma of the cervix.
MedLine Citation:
PMID:  8756019     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two hundred and twenty three cases of squamous cell carcinoma of the cervix were classified according to their resemblance to cells in any of the layers in the ectocervix and a grade of low and high malignancy was also given to each case. Forty cases were classified as basal, 59 as prickle, 115 as intermediate and nine as superficial cell types. Ninety cases were high grade (seven basal, 14 prickle, 63 intermediate and six superficial) and 133 were low grades (33 basal, 45 prickle, 52 intermediate, three superficial). This study shows that the intermediate cell type is the commonest and are usually high grade tumours. The findings also support the idea that squamous cell carcinoma of the cervix may arise from any of the normal layers in ectocervix and suggests that squamous cell carcinoma of the cervix is not a single disease entity, but heterogenous group of tumours like the non-Hodgkin's B cell or T cell lymphomas. Further study is needed to correlate the cytokeratin subtypes and clinical features of each histological type.
Authors:
M Odida; R Schmauz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  East African medical journal     Volume:  73     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-09-26     Completed Date:  1996-09-26     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  S9-10     Citation Subset:  IM    
Affiliation:
Department of Pathology, Makerere University Medical School, Kampala, Uganda.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Squamous Cell / classification*,  etiology,  pathology*
Female
Humans
Incidence
Neoplasm Staging / methods
Prognosis
Reproducibility of Results
Uganda
Uterine Cervical Neoplasms / classification*,  etiology,  pathology*

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