Document Detail


Classic Kaposi sarcoma with sarcoid-like granulomas: a case report and literature review.
MedLine Citation:
PMID:  19679122     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The occurrence of granulomatous reactions within lymph nodes that drain carcinomas is well known but uncommon. Even more rarely, granulomas may occur within the stroma of tumors. These lesions, called sarcoid-like reactions, commonly accompany carcinomas but are very rare in sarcomas. This study presents a case of classic Kaposi sarcoma that contained sarcoid-like granulomas, with a literature review. A soft tissue lesion of the foot was excised from a 74-year-old male. Histopathological examination showed that the tumor tissue consisted of spindle cells, areas of atypical vascular proliferation, and extravasated erythrocytes surrounded by non-caseating granulomas. The patient had no clinical or laboratory findings of sarcoidosis. The case was interpreted as "Kaposi sarcoma containing sarcoid-like granulomas". The association of soft tissue sarcomas with a granulomatous reaction is very rare. A granulomatous reaction is reported to be a good prognostic indicator in several carcinoma types, although its importance in sarcomas is unclear.
Authors:
Nilufer Onak Kandemir; Gamze Yurdakan; Sibel Bektas; Nilgun Solak Tekin
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-08-10
Journal Detail:
Title:  Experimental and molecular pathology     Volume:  87     ISSN:  1096-0945     ISO Abbreviation:  Exp. Mol. Pathol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-28     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370711     Medline TA:  Exp Mol Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-93     Citation Subset:  IM    
Affiliation:
Department of Pathology, School of Medicine, Zonguldak Karaelmas University, 67600, Kozlu, Zonguldak, Turkey. niluferkandemir@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Foot / pathology
Granuloma / pathology*
Humans
Immunohistochemistry
Male
Sarcoma, Kaposi / pathology*
Soft Tissue Neoplasms / pathology*

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